Curriculum Vitae
Christopher A. Warlick, M.D., Ph.D.

Education
Research and Professional Experience
Teaching and Menotoring Experience
Awards
Doctoral Thesis Title
Secured Funding
Bibliography
Research Reports and Refereed Articles
Invited Articles and Book Chapters
Abstracts and Presentations

EDUCATION:

07/2002-06/2007, Urology Resident
Brady Urological Institute
Johns Hopkins Hospital, Baltimore, MD

07/2001-07/2002, General Surgery Intern
Johns Hopkins Hospital, Baltimore, MD

1999-2001, M.D.
University of Minnesota, Minneapolis, MN

1994-1999, Ph.D., Pathobiology
University of Minnesota, Minneapolis, MN

1992-1994, Medical Student
University of Minnesota, Minneapolis, MN

1987-1991, B.A., Biology
Washington University, St. Louis, MO

1984-1987, High School Diploma
Williamsville East High School, East Amherst, NY

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RESEARCH AND PROFESSIONAL EXPERIENCE:

1989-1991, Undergraduate research assistant
Laboratory of Dr. Helen Donis-Keller, Director, Division of Human Molecular Medicine, Department of Surgery, Washington University School of Medicine, St. Louis, MO.  Human genome mapping.

1991-1992, Laboratory technician
Laboratory of Dr. Helen Donis-Keller, Director, Division of Human Molecular Medicine, Department of Surgery, Washington University School of Medicine,St. Louis, MO.  Human genome mapping.

1994-1999, NIH Minority pre-doctoral fellow and graduate student
Laboratory of Dr. R. Scott McIvor, Director, Gene Therapy Program, Institute of Human Genetics and Dept. of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN. Gene transfer/therapy for the in vivo selection of gene-modified cells in the liver and hematopoietic systems.

2004-2007, Research resident
Laboratory of Dr. Angelo DeMarzo, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD and Laboratory of Dr. Ronald Rodriguez, Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD.  Construction and testing in vitro and in vivo of adenoviral vectors for molecular imaging of prostate cancer in mouse models.

2004-present, Reviewer for the journal “Urology”

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TEACHING AND MENTORING EXPERIENCE:

1987-1991, Teaching Assistant for bioethics graduate school course taught by Dr. Helen Donis-Keller, Washington University in St. Louis, MO.

1991-1992, Presented to high school students in the St. Louis, MO area on molecular biology research and the Human Genome Project.

1992-2001, Speaker/panelist addressing various undergraduate student groups through the University of Minnesota College of Biological Sciences and the Office of Diversity in the University of Minnesota Medical School, providing information/advice on graduate and medical school.

1995-1998, Graduate student coordinator and seminar leader for the Summer Undergraduate Research Program, Life Sciences Programs, College of Biological Sciences, University of Minnesota, Minneapolis, MN.

1997-1999, Student recruiter for the University of Minnesota Medical School, Graduate School, and MD/PhD program at the annual research symposium of the Minority Access to Research Careers (MARC) and Minority Biomedical Research Support (MBRS) programs.

1998SP-1999, Tutor for undergraduate students in Vertebrate Physiology and General Biology, University of Minnesota, Minneapolis, MN.

1999, Noon Conference presentation on gene therapy to the departments of Medicine and Medicine-Pediatrics, Regions Hospital, St. Paul, MN.

2000, Clinical evaluator/grader of the observed structured clinical exam (OSCE) for the Clinical Medicine IV course at the University of Minnesota Medical School, Minneapolis, MN.

2001, Student interviewer and student representative on the admissions committee of the University of Minnesota Combined MD/PhD Program, University of Minnesota Medical School, Minneapolis, MN.

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AWARDS:

1986-1987, Induction into National Honor Society

1987-1991,  Recipient of the John B. Ervin full academic scholarship from Washington University in St. Louis, MO

1994-1999, NIH Minority pre-doctoral fellowship providing funding during graduate school studies

1996, Induction into Phi Kappa Phi Honor Society

1997, Winner of Microbiology, Immunology and Molecular Pathobiology graduate student poster contest, Pathobiology division, University of Minnesota, Minneapolis, MN

1999, Recipient of the Minnesota Medical Foundation Jan Lunden Award for research in molecular hepatology

2000, Recipient of the Minnesota Medical Foundation J. Thomas Livermore Award for research in hematology

2001, Recipient of the National Medical Fellowships C. R. Bard Foundation Scholar (national competition) award

2001, Recipient of the Minnesota Medical Foundation Medical Student Achievement Award

2005, First Place in the Frank R. Jones Memorial Resident Research Competition at the urology section of the National Medical Association Annual Meeting

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DOCTORAL THESIS TITLE:

Selective Expansion of Cells Expressing Drug-Resistant Dihydrofolate Reductase Activity.  Defended June 2, 1999. University of Minnesota, Minneapolis, MN

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SECURED FUNDING:

1994-1999, NIH Minority pre-doctoral fellowship.

2005-2006, Funding from the U.S. Department of Defense for research entitled, “Gene Transfer Based Prostate Cancer Imaging.”  Co-investigators: Angelo M. De Marzo, Ronald Rodriguez, Martin G. Pomper, William B. Isaacs.

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BIBLIOGRAPHY

Research Reports and Refereed Articles:

Warlick, C. A., Ramachandra, S., Mishra, S., and Donis-Keller, H.  Dinucleotide repeat polymorphism at the human cardiac -myosin heavy chain gene (HMSYHCO1) locus.  Hum. Molec. Genet. 1:136, 1992.

Donis-Keller, H., Weaver, R., Ramachandra, S., Warlick, C., Burgess, A.K., Weber, J.L., Litt, M., Nickerson, D.A., Boysen, C.A., Hood,L., Mishra, S.K.  A Comprehensive Genetic Linkage Map of the Human Genome (see chromosome 14).  Science 258: 67-86, 1992.

Pandit, SD., Wang, JC., Veile, RA., Mishra, SK., Warlick, CA., Donis-Keller, H.  Index, comprehensive microsatellite, and unified linkage maps of human chromosome 14 with cytogenetic tie points and a telomere microsatellite marker.  Genomics 29 (3): 653-64, 1995.

Vocero-Akbani, A., Helms, C., Wang, JC., Sanjurjo, FJ., Korte-Sarfaty, J., Veile, RA., Liu, L., Jauch, A., Burgess, AK., Hing, AV., Holt, MS., Ramachandra, S., Whelan, AJ., Anker, R., Ahrent, L., Chen, M., Gavin, MR., Iannantuoni, K., Morton, SM., Pandit, SD., Read, CM., Steinbrueck, T., Warlick, C., Smoller, DA., Donis-Keller, H.  Mapping human telomere regions with YAC and P1 clones: chromosome-specific markers for 27 telomeres including 149 STSs and 24 polymorphisms for 14 proterminal regions.  Genomics 36 (3): 492-506, 1996.

Christopher A. Warlick, Colin L. Sweeney, and R. Scott McIvor.  Maintenance of Differential Methotrexate Toxicity Between Cells Expressing Drug-Resistant and Wild-Type Dihydrofolate Reductase Activities in the Presence of Nucleosides Through Nucleoside Transport Inhibition.  Biochem Pharm 59 (2):141-151, 2000.

Rohaizah James, Christopher Warlick, Miechaleen Diers, Roland Gunther and R. Scott McIvor.  Mild Preconditioning and Low-level Engraftment Confer Methotrexate Resistance in Mice Transplanted with Marrow Expressing Drug-Resistant Dihydrofolate Reductase Activity.  Blood 96 (4): 1334-41, 2000. 

William F. Kaemmerer, Rukmini G. Reddy, Christopher A. Warlick, Seth D. Hartung, R. Scott McIvor, and Walter C. Low.  In vivo Transduction of Cerebellar Purkinje Cells using Adeno-Associated Virus Vectors.  Molecular Therapy 2 (5): 446-457, 2000.

Christopher A. Warlick, Miechaleen D. Diers, John E. Wagner and R. Scott McIvor.  In vivo Selection of Drug-Resistant Transgenic Hematopoietic Stem Cells in a Murine Bone Marrow Transplant Model. J of Pharmacology and Experimental Therapeutics 300 (1): 50-56, 2002.

Christopher A. Warlick, Ranjiv Mathews, Arlene C. Gerson.  Keeping Childhood Sexual Abuse on the Urologic Radar Screen.  Urology 66: 1143-1149, 2005.

Christopher Warlick, Bruce J Trock, Patricia Landis, Jonathan I Epstein, H. Ballentine Carter.  Delayed versus immediate surgical intervention and prostate cancer outcome.  J National Cancer Institute 98: 355-357, 2006.

Christopher A. Warlick, Guilherme C. Lima, Mohamad E. Allaf, Ioannis Varkarakis, Sompol Permpongkosol, Edward M. Schaeffer, Louis R. Kavoussi, Thomas W. Jarrett, Stephen B. Solomon.  Clinical Sequlae of Radiographic Iceball Involvement of the Collecting System During CT-Guided Percutaneous Renal Tumor Cryoablation.  Urology 67: 918-922, 2006.

Ganesh S. Palapattu, Alan Meeker, Timothy Harris, Michael I. Collector, Saul J. Sharkis, Angelo M. DeMarzo, Christopher Warlick, Charles G. Drake, and William G. Nelson.  Epithelial Architectural Destruction is Necessary for Bone Marrow Derived Cell Contribution to Regenerating Prostate Epithelium.  J Urology  In Press.  2006.

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Invited Articles and Book Chapters:

Christopher A. Warlick, Mohamad E. Allaf, H. Ballentine Carter.  Expectant treatment with curative intent in the prostate-specific antigen era: triggers for definitive therapy. Urologic Oncology 24: 51-57, 2006.

Christopher A. Warlick.  Acute Gross Hematuria: Etiology and Management.  The Brady Urology Manual.  Parsons, J.K. and Wright, E.J. (eds.).  Taylor and Francis Group Abington, Oxon, UK.  2006.

Christopher A. Warlick, David Y. Chan.  Laparoscopic Renal Biopsy: Technique and Results.  Textbook of Laparoscopic Urology.  Gill, I. (ed.) Marcel Dekker, NY, NY.  In Press. 2006.

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Abstracts and Presentations:

Warlick, C., Lairmore, T.C., Mishra, S.K., Holt, M.S., and Donis-Keller, H. 1990.  Isolation of a YAC clone from D14S26 near a gene for familial hypertrophic cardiomyopathy and identification of two new RFLP probes at this locus.  Platform presentation at the American Society of Human Genetics Meeting, Cincinnatti, OH.  Abstr: Amer. J. of Hum. Genet. Suppl 47:A203, 0798. 

Warlick, C., and R.S. McIvor.  1997.  In vivo selection of drug-resistant hepatocytes in a regenerating mouse liver model.  Keystone Symposia on Cell and Molecular Biology E6:  353.

Warlick, C., Sweeney, C., R. S. McIvor. 1998. Effect of nucleosides and nucleoside transport inhibitors on WT and methotrexate-resistant DHFR-expressing cells: implications for gene therapy.  Keystone Symposia on Cell and Molecular Biology J7: 357

R. Scott McIvor, Lalitha Belur, Miechaleen D. Vagt, and Christopher Warlick.  1999.  An interstrain transgenic mouse system for tracking hematopoietic cells during selective antifolate-mediated expansion in vivo.  Keystone Symposia on Cell and Molecular Biology.  A4: 320.

Christopher A. Warlick, Miechaleen Diers, Cindy Eide, Lalitha Belur, and R. Scott McIvor. 1999.  In Vivo Selection of DHFR-Transgenic Cells. 3rd Annual Meeting American Society of Gene Therapy.  Abst # 294

Kaemmerer, W.F., Reddy, R., Warlick, C., McIvor, R.S., and Low, W.C.  1999.  Adeno-associated virus (AAV) as a means for in vivo gene delivery to cerebellar Purkinje cells.  29th Annual Meeting of the Society for Neuroscience.  Abst # 798.

Christopher A. Warlick, Ranjiv Mathews, Arlene Gerson.  Maintaining vigilance for child sexual abuse. J Urology 173 (4 supp): 215.  2005.

Guilherme C. Lima, Christopher A. Warlick, Mohamad E. Allaf, Ioannis M. Varkarakis, Sahar Kohanim, Myrna Sroka, Sompol Permpongkosol, Louis R. Kavoussi.  Postchemotherapy laparoscopic retroperitoneal lymph node dissection: evolution of a technique.  J Urology 173 (4 supp): 226. 2005.

Christopher A. Warlick, Guilherme C. Lima, Mohamad E. Allaf, Ioannis M. Varkarakis, Louis R. Kavoussi, Thomas W. Jarrett, Stephen B. Solomon.  Collecting system involvement during renal tumor cryoablation.  J Urology 173 (4 supp): 263.  2005.

Ajay Gupta, Mohamad E. Allaf, Christopher A. Warlick, Thomas W. Jarrett, David Y. Chan, Louis R. Kavoussi, Stephen B. Solomon.  Percutaneous renal tumor cryoablation under CT guidance: initial clinical experience.  J Urology 173 (4 supp): 413.  2005.

Christopher A. Warlick, Guilherme C. Lima, Mohamad E. Allaf, Sam B. Bhayani, Ioannis M. Varkarakis, Louis R. Kavoussi, Thomas W. Jarrett, Stephen B. Solomon.  Percutaneous renal tumor cryoablation (video). J Urology 173 (4 supp): 429.  2005.

Christopher A. Warlick, Angelo M. De Marzo, William B. Isaacs, Martin G. Pomper, Ronald Rodriguez.  Toward AMACR-based molecular imaging of prostate cancer.  Annual Meeting of the National Medical Association Urology Section.  2005.

Christopher A. Warlick, Bruce J. Trock, Patricia K. Landis, Jonathon I Epstein, H. Ballentine Carter.  Pathological outcomes are similar for men in an expectant management program undergoing delayed surgical intervention compared to those undergoing immediate intervention.  J Urology 175 (4 supp): 211.  2006.

Christopher A. Warlick, Martin G. Pomper, William B. Isaacs, Angelo M. DeMarzo, Ronald Rodriguez.  Alpha-Methylacyl-CoA Racemase (AMACR)-based molecular imaging of prostate cancer.  J Urology 175 (4 supp): 501.  2006.

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